IBL- America's Nfatc1 Anti-Human Antibody (Clone At1C3) is a Mouse monoclonal antibody. The Nfatc1 Anti-Human Antibody (Clone At1C3) was generated using NFATC1 as the antigen. It reacts with Homo Sapiens, and Human. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, and Western Blot.
Description
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1(NFATc1) is a component of the nuclear factor of activated T cells DNA-binding transcription complex which consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. This protein plays a main role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription and functions as a major molecular target for the immunosuppressive drugs such as cyclosporine A. NFATc1 is expressed in most human primary lymphocytes and mature human T- and B-cell neoplasms